Mal to Harken in Bushwhacked when Harken uncuffs Mals hands from behind his back then recuffs 'em in front 
Next up:
“Well, it wasn’t really broke.”
Kaylee in Out of Gas, right after Mal caught Bester um, twixit her nethers lol…
Up Next:
Hey. You’re part of my crew.
_
Second to last scene (the penultimate if you will) of Safe. One of my favorite moments. “Why are we still having this conversation?”
Next up:
“Who will see the unholy truth, the only captured specimen – in existence – of Alien life!”
haven’t we done this scene already?
barker, The Message, attempting to draw an adequate crowd for Dead Bessie
“That’s the problem about picking up tourists. Ain’t never what they claim to be.”
Apologies if it has…I haven’t read the thread end-to-end
Jeebus, there’s only twelve episodes (Plus a movie, and DVD extras which get me in trouble for quoting…)
This is stumping me Lady D… was it in the series or in a script? a hint would be helpful lol… unless of course someone else knows the answer, then I wouldnt need a clue now would I…
awwww Pike, nobody was gettin you in trouble ;)… its just a game afterall… I actually liked the River Tam sessions quote you laid down… One of the best I have ever seen played in this game… My only regret is that I did’t think of it first lol…
Jayne, Safe in Alliance cruiser, Book on the operating table:
Next up (hope it hasn’t been done yet)
<cracks knuckles>
It ain’t a hand of cards. It’s called a life. I’ve got a better life than you. And that’s just barely, and just cause I don’t spend my every waking hour pissing all over it, like some folks I’m holdin’ a gun on
Mal to Yosafbridge in Trash
Next up:
“Big mosquito”
(sorry) :o
awwww… that was when Kaylee got <sniff> shot and Mal said it aint nothing but a mosquito bite in the pilot ep… the real pilot… not the rushed one they aired in its place…
Up Next:
Aaaww dirty, dirty whore!
_
Do not give it a second thot buddy.
Mal to a retreatin’ Yosafbridge after she leaves his sexy ass naked and stranded in Trash
Next:
“Yeah, but… uh, there’s stuff to do.”
Bester to Mal after he finished knockin boots :5 
with Kaylee in OOG…
Up next:
Someone respectable enough might be able to.
_
That’s Book, to Wash, Inara, Simon & Kaylee in The Train Job when they’re tryin’ to figure out how to rescue Mal & Zoe
Next:
“We got outflanked by the independent squad, and we’re never gonna make it back to our platoon.”
‘Safe’. In a flashback, River is playing and talking to Simon.
“Will you wash it first?”
Inara to Mal, Heart of Gold, when he asks if she’ll be on his arm at the theater as he sizes up the enemy
“I’m praying for you”
Inara to Mal in Serenity, as she’s setting the flash-bang incense?*
“Now there’s the smile made of sunlight.”
*Where does one obtain that, BTW?
Atherton Wing to Inara at the beginning of Shindig
Next:
“That’s assuming there’s a head.”
oops
10 char